Mastercard international interchange rates are the fees paid by an acquiring bank to a card-issuing bank when a merchant accepts a Mastercard issued in a different country or region. This guide provides a detailed breakdown of these interregional costs, how they differ from domestic rates, and the strategic steps businesses can take to manage high cross-border processing expenses. Expert Verified & Fact-Checked From the Desk of: Chris DuPont, a veteran of Merchant Statement A